Molecular mechanisms of axon guidance
نویسندگان
چکیده
منابع مشابه
Molecular mechanisms of axon guidance.
In order to form a functional nervous system, neurones extend axons, often over long distances, to reach their targets. This process is controlled by extracellular receptors and their ligands, several families of which have been identified. These proteins may act to either repel or attract growth cones and a given receptor may transduce either type of signal, depending on the cellular context. ...
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PROTEINS THAT PROMOTE NEURITE OUTGROWTH ............................................................ 119 Soh~ble Neurotrophic Agents .................................................................................... 122 ECM Proteins .......................................................................................................... 123 CAMs .................................................
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of a very exciting and intensive meeting that took place The workshop, entitled " Molecular Biology of Axon Guidance, " gathered a forum of 26 speakers and some Spain 90 people in total, who enthusiastically presented and discussed the recent advances in the field. I will summarize the meeting in this review, emphasizing some of the More than a century ago, Cajal published one of his new data p...
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Axon guidance plays a key role in establishing neuronal circuitry. The motile tips of growing axons, the growth cones, navigate by responding directionally to guidance cues that pattern the embryonic neural pathways via receptor-mediated signaling. Evidence in vitro in the last decade supports the notion that RNA-based mechanisms contribute to cue-directed steering during axon guidance. Differe...
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210,670 (1995); J. Massague, Cell 85, 947 (1996). 72. T. Lecuit et al., Nature 381, 387 (1996); D. Nellen, R. Burke, G. Struhl, K. Basler, Cell 85, 357 (1996). 73. K. M. Reilly and D. A. Melton, Cell 86, 743 (1996). 74. B. A. Parr, M. J. Shea, G. Vassileva, A. P. McMahon, Development 119, 247 (1993); M. Hollyday, J. A. McMahon, A. P. McMahon, Mech. Dev. 52, 9 (1995). 75. M. E. Dickinson, R. Kru...
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ژورنال
عنوان ژورنال: Developmental Biology
سال: 2006
ISSN: 0012-1606
DOI: 10.1016/j.ydbio.2005.12.048